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Nanjing Bangnuo Biotechnology Co., Ltd.

Pimobendan, 74150-27-9, Cardiotonic Agent manufacturer / supplier in China, offering Pimobendan for Cardiotonic Agent and Antiviral 74150-27-9, Nanjing Bangnuo Sex Hormones Addyi / Flibanserin (167933-07-5) for Treating Depression, Weight Loss Powder 94-07-5 Bitter Orange / Synephrine (API) for Sale and so on.

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Pimobendan for Cardiotonic Agent and Antiviral 74150-27-9

Purchase Qty.:
(g)
1-9 10+
FOB Unit Price: US $1 US $2
Purchase Qty. (g) FOB Unit Price
1-9 US $1
10+ US $2
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Production Capacity: 3000kg/Month
Transport Package: 10g/100g/1000g
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: 74150-27-9
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Market: Worldwide
  • Specification: 74150-27-9
  • HS Code: 3001200090
  • Powder: Yes
  • Certification: ISO 9001
  • State: Solid
  • Sample: Free
  • Trademark: NJBNSTEROID
  • Origin: Made in China
Product Description
Pimobendan For Cardiotonic Agent And Antiviral 74150-27-9


Product Name: Pimobendan 
Synonyms: PIMOBENDAN;4,5-dihydro-6-[2-(4-methoxyphenyl)-1h-benzimidazol-5-yl]-5-methyl-3(2h)-pyridazinone;PIMOBENDANE HCL;Pimobendam;3(2H)-Pyridazinone, 4,5-dihydro-6-2-(4-methoxyphenyl)-1H-benzimidazol-5-yl-5-methyl-;3(2H)-Pyridazinone, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl- (9CI);dl-Pimobendan;Racemic pimobendan 
CAS: 74150-27-9 
MF: C19H18N4O2 
MW: 334.37 
Chemical Properties White Solid 
Usage antiviral 
Usage Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction. 

COA
 
Items of analysisSpecificationResults
AppearanceLight yellow to off-white solidConforms
IdentificationIR/HPLCConforms
Water≤0.2%0.12%
ImpuritySingle impurity ≤ 0.1%0.05%
Purity≥99.5%99.9%
ConclusionQualified

Mechanism of action

Pimobendan is a positive inotrope (increases myocardial contractility). It sensitizes and increases the binding efficiency of cardiac troponin in the myofibril to the calcium ions that are already present in systole. In normal hearts it increases the consumption of oxygen and energy to the same degree as dobutamine but in diseased hearts it may not. Pimobendan also causes peripheral vasodilation by inhibiting the function of phosphodiesterase III. This results in decreased resistance to blood flow through systemic arterioles, which decreases afterload (decreases the failing heart's workload) and reduces the amount of mitral regurgitation.


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